The Full form of ISCS is Interval-Specific Congenic Strains. ISCS allows the mapping of quantitative trait locus(QTL) into a 1-cM interval. This entire experimental design is a series of strains refer as Interval-Specific Congenic Strains. Each ISCS is referring to recombinant at a very specific 1-cM sub-interval. This will combine together to comprise a wider interval, with a QTL, which was mapped earlier.
Accuracy of 1-Cm mapping into intervals can be done by particularly and previously detected QTL. These QTL can be of moderate pr small effect involving a number of less than 1000 personnel. Additionally, it seems like to posItion cloning of a QTL, Interval-Specific Congenic Strains can do better and serve as the ultimate genetic mapping process rather than physical mapping.
Interval-Specific Congenic Strains is known as ISCS. It lets the plotting of measurable trait locus into a 1-cm interval. Accuracy of 1-Cm mapping into gaps can be done by chiefly and previously detected QTL. Congenic is generally mentioned when two bacteria differ in one locus and a linked segment of the chromosome in genetics.
Congenic is generally referred to as when two organisms differ in one locus and a linked segment of the chromosome in genetics. Subsequently, Coisogenic does not apply in the surrounding chromosome but differs perfectly in one locus only.
Congenic organisms, can be bred and only occur through spontaneous or targeted mutation at the locus. On the contrary coisogenic organisms do not have the application to do the same. Furthermore, the Recipient strain process refers to when two inbred strains can be mated (like rats or mice) in the laboratory to generate Congenic strains & backcross the descendants 5-10 generations with one of the original strains.
A common innovative design that provides a mapping of a quantitative characteristic locus (QTL) into a 1-cM interval is performed. The design consists of a set of strains, termed “interval-specific congenic strains (ISCS)”. Each ISCS is recombinant at a specific 1-cM sub-interval out of an established set of sub-intervals, which collectively constitute a wider interval, to which a quantitative characteristic locus was earlier mapped.
Congenic strains contain a discrete DNA region derived from another strain. In general, 10 generations of backcrossing is considered the standard for congenic strain development. The process can be further aided by the superovulation of females, to produce many more eggs. The optimal mating scheme for individual congenic lines will vary.
There exists one more strain called syngenic strains. Syngenic strains are genetically identical and compatible in terms of immunology. This results in allowance to transplantation. On the other hand, Congenic strains are genetically identical but have a variation in certain areas. There is a difference between Syngenic strains and Congenic strains.
| Term | Full Form |
| ISCS | Interval-Specific Congenic Strains |
FAQ’s
ISCS allows the mapping of quantitative trait locus(QTL) into a 1-cM interval. This entire experimental design is a series of strains refer as Interval-Specific Congenic Strains.
ISCS is short form of Interval-Specific Congenic Strains.
Interval-Specific Congenic Strains is full form of ISCS.
People May Also Check
| PT Full Form | PTCA Full Form |
| RAM Full Form | RAW Full Form |
| RD Full Form Full Form | RDW Full Form |
| RNA Full Form | RO Full Form |
| RSVP Full Form | RTA Full Form |